New informative article: "Better Sleep Could Help Your Brain Flush Out Dementia-Linked Toxins". This well-written description of glymphatic clearance recently published in Science Direct gives readers a deep dive into how improving sleep can reduce the risk for Dementia.

The lengthy study by authors Lutz, Harkotte, and Born states, in the abstract, "A promising new area arising from this research pertains to brain-stimulation techniques developed to enhance memory consolidation during human sleep."

Neurosom’s CEO Viral Sheth and our founder and chairman Don Tucker shared their vision for Sleep Therapy and reducing dementia risk with this group supporting business through innovative research.

A terrific article in last month’s Scientific American highlights the connection between poor-quality sleep and a heightened risk of dementia.

Here, Dr. Rhonda Patrick explains the link between poor sleep and an increased risk for dementia, and what the phrase glymphatic clearance means.

BEL Webinar: Investigating the Role of Sleep In Parkinson's Disease Using the Sleep WISP™. August 29th, 10am PT, 1pm ET.

Scientists studied EEG patterns in elderly subjects and, with the assistance of AI, found a correlation between irregular EEG activity and mild cognitive impairment. The future utility of EEG in the detection of neurodegenerative illness opens an area of keen interest, as current diagnostic methods often do not detect MCI until it has progressed to dementia. Read the article: https://lnkd.in/eNuMyiwj

Register at: https://lnkd.in/gB7-bhSc for tomorrow's webinar - May 20th, 8 am PST, 11 am EST, "Use FLOW in your lab to convert scripts into a reproducible, single-click workflow", Featuring Dr. Jhunlyn Lorenzo, Post Doctoral Researcher at the Cognitive Neuroimaging lab (UNICOG) and Neurospin (France), and Roma Shusterman, our Chief Technology Officer at BEL. They will demonstrate how the NeuroSpin lab developed a MATLAB-based EEG analysis pipeline (APICE) and used FLOW to containerize it into a reproducible, single-click workflow. This 45-minute webinar includes a live demo and 10-15 minutes of Q&A at the end.

NEAT uses artificial intelligence (AI) to classify sleep stages from the sleep EEG accurately. It can be used in two modes: online (near-real time) and offline. Neurosom™, the BEL partner company that provides personalized closed-loop neuromodulation therapy to lower the risk of dementia, uses NEAT as a core part of its technology.

Neurosom™ will be presenting at LSI USA ‘25, taking place March 17-21 at the Waldorf Astoria Monarch Beach Resort & Club in Dana Point, California. During the event, Neurosom’s CEO, Viral Sheth, will present the Sleep WISP™ device, a personalized neuromodulation therapy to reduce the risk of dementia.

Roma Shusterman, Allison C. Waters, Shannon O’Neill, Marshall Bangs, Phan Luu, and Don M. Tucker published “An active inference strategy for prompting reliable responses from large language models in medical practice” in the renowned journal Digital Medicine.

We are thrilled to announce that Neurosom has been selected to pitch at the MedTech Innovator West Coast Pitch Event this March 5th and 6th! We’re excited to showcase our innovation in medtech and share how we’re making an impact. Viral Sheth, COO, will speak about our innovative Sleep WISP technology at the largest accelerator for medical device companies. Looking forward to connecting with judges, investors, and fellow entrepreneurs. See you there!

BEL recently supported groundbreaking research using its 280-channel Whole Head EEG system. Drs. Muthuraman Muthuraman & Manuel Bange, along with BEL's Chief Operating Officer, Viral Sheth, visited Dr. Simon Little’s Movement Disorders and Neuromodulation Center in San Francisco to collect multimodal wireless HD EEG, EMG, ECG data from over a dozen Parkinson’s disease patients. These patients, equipped with the latest bi-directional DBS system and intracranial electrodes, participated in studies to better understand the circuits and signals underlying their symptoms.

Following the success of receiving FDA 510(k) clearance for its SOURCERER source estimation software in October 2024, BEL submitted its NEAT sleep staging software for FDA review and approval for 510(k) clearance. NEAT is an innovative medical device software application that uses machine learning to streamline identification of different sleep stages post EEG-acquisition.

NATO: "HUMAN DIGITAL TWIN IN THE MILITARY: Findings and Perspective." During this conference Dec. 10-12 in Orlando, Florida, BEL and Neurosom Chief Scientist Dr. Phan Luu will present a paper titled, "Electrocortical Neuromorphic Augmented Cognition Transmission (ENACT) for Human Digital Twin Communication". Dr. Luu will propose a new technology (ENACT) that draws on current HD EEG and Individual Head Model brain mapping, Machine Learning sleep staging classification, Transcranial Electrical Stimulation (TES), and current and future AI digital twin technologies to provide augmented cognitive human performance during military operations.

BEL and Neurosom Chief Science Officer, Dr. Phan Luu, PhD, will be presenting a talk "Transcranial Electrical Stimulation (TES) targeting limbic cortex increases the duration of human deep sleep" at the UK Royal Society Meeting in London on November 26th. (10:30-10:50 am ET) Dr. Luu's talk will present evidence that slow-wave sleep can be enhanced using BEL's Sleep WISP - a portable, user-friendly device deployed in the home. The ability to selectively enhance slow-wave sleep has significant health implications. The lecture is free to attend online but participants must register ahead of time.

Neurosom's Chief Operating and Strategy Officer Viral Sheth joined Health Tech Strategies CEO Suzy Engwall for an episode of "Med Tech Minis" to chat about the progress Neurosom has made with Sleep Therapy, our clinical trial, and a hint about AI integration that will be a big story for us in 2025.

As part of a larger conference organized by the Biosignals Technical Committee of Germany. As part of a lecture on biomedical and electrophysiological movement analysis, our Chief Operating and Strategy Officer, Viral Sheth, will give a talk titled Advancing Neurotechnology: Shaping the Future of Sleep and Brain Health with BEL's EEG System One and Sleep WISP, on November 15, 10:30am PT, which will be streamed live from Augsburg, Germany.

BEL receives FDA 510(k) clearance for SOURCERER source estimation software. “SOURCERER is a next generation software that combines an elegant and easy user interface with a faster analysis, precise results, and a managed workflow. As a stand alone software tool, or seamlessly integrated with BEL EEG System One and FLOW product EcoSystem, SOURCERER is an indispensable part of the source estimation toolkit,” adds Dr. Phan Luu, Chief Scientific Officer.

Thank you to our distributor @Neurolite for featuring BEL products at the 2024 DACH annual congress earlier this month, the German-Austrian-Swiss working group on epilepsy. The BEL EEG System One and now FDA 510(k) cleared SOURCERER source estimation software work together seamlessly to provide a complete source estimation toolkit.